A weary parent walks into your urgent care clinic, eyes heavy from too many sleepless nights. “This cough just won’t go away,” they say. The child beside them is tired too—persistent, wet coughing for weeks, difficulty keeping up with peers, and no end in sight.
Sound familiar? If you haven’t already considered protracted bacterial bronchitis (PBB), now’s the time.
Protracted bacterial bronchitis is one of the most common causes of chronic cough in children—especially preschoolers.
It’s defined by a wet, productive cough lasting more than four weeks in the absence of other underlying conditions. You might also see it described as persistent bacterial bronchitis, chronic suppurative lung disease, or even childhood chronic bronchitis.
Bronchiolitis, typically caused by viruses like RSV, is viral by definition. In contrast, PBB is a bacterial infection that takes root in the bronchi, often following viral infections that damage airway lining. The distinction matters—while bronchiolitis doesn’t respond to antibiotics, PBB does.
The leading theory is that frequent viral infections (hello, daycare!) damage the airway lining, allowing bacteria to stick around and multiply. The result: prolonged bronchitis symptoms like a rattling cough and mucus production.
Risk factors include:
Interestingly, kids with asthma, reactive airway disease, or bronchiolitis may actually have a decreased risk for PBB—but misdiagnosis is still common.
PBB is a major cause of ongoing cough in kids. But it’s often mistaken for asthma, which leads to treatment with corticosteroids—ineffective for PBB.
Here’s how they differ:
Feature |
PBB |
Asthma |
Cough type |
Wet, all day |
Dry, mostly nocturnal |
Chest sounds |
Rattle (from secretions) |
Wheeze (from bronchospasm) |
Breathlessness |
Related to coughing fits |
Independent of cough |
Response to treatment |
Antibiotics |
Inhaled corticosteroids |
More than 60% of PBB cases resolve after a two-week course of antibiotics. Catch it early, and you’ll avoid unnecessary asthma meds—and potentially prevent progression to chronic bronchitis or bronchiectasis.
By recognizing and managing PBB effectively, clinicians can help put an end to the cough that just won’t quit—and ensure better long-term respiratory health for our youngest patients.